Daret K St Clair Selected Research

Superoxide Dismutase

1/2019	UVB-induced inactivation of manganese-containing superoxide dismutase promotes mitophagy via ROS-mediated mTORC2 pathway activation.
7/2015	Manganese superoxide dismutase promotes interaction of actin, S100A4 and Talin, and enhances rat gastric tumor cell invasion.
4/2014	FUsed in sarcoma is a novel regulator of manganese superoxide dismutase gene transcription.
1/2013	p53 regulation of energy metabolism and mitochondria regulation of p53 in cancer cells: an insight into the role of manganese superoxide dismutase.
6/2012	Manganese superoxide dismutase regulation and cancer.
11/2011	Manganese superoxide dismutase is a p53-regulated gene that switches cancers between early and advanced stages.
7/2010	RelB regulates manganese superoxide dismutase gene and resistance to ionizing radiation of prostate cancer cells.
12/2008	Mutations in the SOD2 promoter reveal a molecular basis for an activating protein 2-dependent dysregulation of manganese superoxide dismutase expression in cancer cells.
8/2008	SN52, a novel nuclear factor-kappaB inhibitor, blocks nuclear import of RelB:p52 dimer and sensitizes prostate cancer cells to ionizing radiation.
9/2007	The radiosensitization effect of parthenolide in prostate cancer cells is mediated by nuclear factor-kappaB inhibition and enhanced by the presence of PTEN.

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Daret K St Clair Research Topics

Disease

53	Neoplasms (Cancer) 06/2022 - 05/2002
11	Prostatic Neoplasms (Prostate Cancer) 01/2017 - 07/2007
8	Cardiotoxicity 01/2018 - 09/2004
7	Carcinogenesis 01/2019 - 01/2003
7	Chemotherapy-Related Cognitive Impairment 01/2017 - 11/2005
6	Cardiomyopathies (Cardiomyopathy) 10/2020 - 02/2006
5	Mitochondrial Diseases (Mitochondrial Disease) 10/2020 - 03/2006
5	Cognitive Dysfunction 01/2019 - 02/2007
5	Alzheimer Disease (Alzheimer's Disease) 11/2011 - 03/2006
2	Lymphoma (Lymphomas) 01/2019 - 01/2012
2	Breast Neoplasms (Breast Cancer) 01/2017 - 11/2005
2	Heart Failure 02/2016 - 02/2012
2	Leukemia 01/2016 - 06/2012
2	Hepatocellular Carcinoma (Hepatoma) 08/2012 - 05/2005
2	Fatigue 11/2011 - 12/2009
2	Body Weight (Weight, Body) 11/2011 - 02/2007
2	Muscle Weakness 11/2011 - 12/2009
2	Lung Neoplasms (Lung Cancer) 12/2010 - 09/2009
1	Cardiovascular Diseases (Cardiovascular Disease) 10/2020
1	Tuberous Sclerosis (Bourneville's Disease) 01/2019
1	Myelodysplastic Syndromes (Myelodysplastic Syndrome) 09/2017
1	Radiation Injuries (Radiation Sickness) 01/2017
1	Inflammation (Inflammations) 01/2017
1	Stomach Neoplasms (Stomach Cancer) 07/2015
1	Spinal Cord Injuries (Spinal Cord Injury) 05/2014
1	Sarcoma (Soft Tissue Sarcoma) 04/2014
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 12/2010

Drug/Important Bio-Agent (IBA)

20	Superoxide DismutaseIBA 01/2019 - 05/2002
19	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2019 - 09/2004
16	Proteins (Proteins, Gene)FDA Link 01/2019 - 06/2004
15	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2019 - 06/2004
15	AntioxidantsIBA 01/2019 - 06/2004
9	Pharmaceutical PreparationsIBA 01/2019 - 11/2005
7	EnzymesIBA 01/2019 - 06/2004
6	NF-kappa B (NF-kB)IBA 07/2010 - 07/2007
4	Amyloid (Amyloid Fibrils)IBA 11/2011 - 03/2006
3	Glutathione (Reduced Glutathione)IBA 01/2019 - 02/2007
3	Biological ProductsIBA 11/2018 - 08/2008
3	LuciferasesIBA 01/2012 - 12/2010
3	AndrogensIBA 04/2010 - 07/2007
3	Amyloid beta-PeptidesIBA 11/2008 - 03/2006
2	Indicators and Reagents (Reagents)IBA 01/2022 - 01/2012
2	4-hydroxy-2-nonenal (4-hydroxynonenal)IBA 01/2018 - 06/2004
2	Superoxides (Superoxide)IBA 09/2017 - 01/2006
2	Free RadicalsIBA 09/2017 - 11/2005
2	CytokinesIBA 01/2017 - 01/2017
2	Blood Proteins (Serum Proteins)IBA 10/2015 - 06/2011
2	DNA (Deoxyribonucleic Acid)IBA 04/2014 - 09/2007
2	Oxygen (Dioxygen)IBA 05/2013 - 09/2004
2	multidrug resistance-associated protein 1IBA 04/2012 - 11/2006
2	Interleukin-8 (Interleukin 8)IBA 01/2012 - 04/2009
2	Prostate-Specific Antigen (Semenogelase)IBA 01/2012 - 04/2010
2	Acetates (Acetic Acid Esters)FDA Link 11/2011 - 08/2006
2	AnthracyclinesIBA 11/2011 - 06/2011
2	Acetylcysteine (Siran)FDA LinkGeneric 11/2011 - 09/2010
2	Deoxyglucose (2 Deoxy D glucose)IBA 12/2010 - 09/2009
2	parthenolideIBA 04/2010 - 09/2007
2	Transcription Factors (Transcription Factor)IBA 04/2008 - 01/2003
2	Presenilin-1IBA 05/2006 - 03/2006
2	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2006 - 06/2004
1	Biomarkers (Surrogate Marker)IBA 06/2022
1	AldehydesIBA 10/2020
1	NexusIBA 10/2020
1	Mechanistic Target of Rapamycin Complex 1IBA 01/2019
1	Choline (Choline Chloride)IBA 01/2019
1	GlutaredoxinsIBA 01/2019
1	PeroxiredoxinsIBA 01/2019
1	ManganeseIBA 01/2019
1	Reactive Nitrogen SpeciesIBA 01/2019
1	Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric 11/2018
1	CatalaseIBA 01/2018
1	withaferin AIBA 09/2017
1	quinone (benzoquinone)IBA 09/2017
1	Sirtuin 3IBA 01/2017
1	Ascorbic Acid (Vitamin C)FDA LinkGeneric 01/2017
1	Transcription Factor RelBIBA 01/2017
1	SirtuinsIBA 01/2017
1	Glutathione Disulfide (GSSG)FDA LinkGeneric 01/2016
1	arjunolic acidIBA 11/2015
1	Sulfhydryl Compounds (Thiols)IBA 07/2015
1	TalinIBA 07/2015
1	Mn(III) meso- tetrakis(N- n- butoxyethylpyridinium- 2- yl)porphyrinIBA 05/2014
1	CalciumIBA 05/2014
1	RNA-Binding Proteins (RNA-Binding Protein)IBA 04/2014
1	thiaminase II (thiaminase)IBA 06/2012
1	Thiamine (Aneurin)FDA Link 06/2012
1	Thiamine PyrophosphateIBA 06/2012
1	Peptides (Polypeptides)IBA 11/2011
1	Drinking WaterIBA 11/2011
1	ChromatinIBA 11/2011
1	MicroRNAs (MicroRNA)IBA 12/2010
1	Adenosine Triphosphate (ATP)IBA 12/2010
1	NADPH Oxidases (NAD(P)H oxidase)IBA 04/2010
1	Tyrosine Kinase InhibitorsIBA 04/2010
1	SesquiterpenesIBA 04/2010
1	LactonesIBA 04/2010
1	Phosphotransferases (Kinase)IBA 04/2010

Therapy/Procedure

14	Therapeutics 06/2022 - 07/2007
11	Drug Therapy (Chemotherapy) 01/2019 - 02/2007
8	Radiotherapy 01/2017 - 09/2007